THROMBOSIS : Advancing Research in the Fight Against Blood Clots and related complications with our Thrombosis Models
Porsolt offers comprehensive thrombosis models designed to assess the impact of compounds and potential therapies on blood flow dynamics. Each one of our thrombosis models enable the investigation of direct effects, confounding factors, and side effects related to specific treatments on blood flow regulation.
With a dedicated focus on thrombosis research, our models serve as invaluable tools for investigating a range of thrombotic events. From ex vivo models of thrombosis to specialized lab tests for deep vein screening, our solutions provide insights into the intricate mechanisms underlying clot formation and blood flow disruptions.
SCROLL
THROMBOSIS
| Endothelial cell activation/ Drug-Induced Vascular Injury (DIVI) | HUVECs cells |
| Arterial thrombosis (FeCl2) | Rat |
| Arterio-venous shunt (silk thread model) | Rat |
| Bleeding time (anesthetized animal) | Rat |
| Venous thrombosis (FeCl2) | Rat |
| PLATFORM | BIOMARKER | SPECIES (SAMPLE) |
|---|---|---|
| Coagulation | APTT (Activated Partial Thrombin Time) | Multiple species |
| Prothrombin time | Multiple species | |
| Fibrinogen | Multiple species | |
| Hematology | Complete Blood Count: - Red blood cells: hemoglobin, hematocrit, mean cell volume, mean cell hemoglobin concentration, platelets - White blood cells: lymphocytes, neutrophils, eosinophils, basophils, monocytes | Multiple species |
| CBA - ELISA - WB - IHC-PIHC-Fr - ICC - HTRF | Other targets upon request | Multiple species & biological specimens |
Precision in Deep Vein Thrombosis Assessment
Deep vein thrombosis (DVT) is a significant concern, requiring accurate assessment methods for timely intervention. Porsolt’s expertise extends to deep vein thrombosis models, offering refined methodologies that enable researchers to identify DVT risk factors and assess potential treatments. By combining advanced techniques with our thorough understanding of coagulation pathways, Porsolt contributes to the advancement of DVT diagnostics and management.
In tandem with our advanced testing methodologies, our team of experienced researchers employs deep vein thrombosis histology and bioanalysis techniques to delve deeper into the histopathological aspects of thrombosis. By analyzing tissue samples l, we unravel the complexities of thrombotic events, aiding in the identification of underlying factors and contributing to the development of targeted therapeutic strategies.
At Porsolt, we understand the urgency of thrombosis research and its critical role in improving patient outcomes. Our expertise extends beyond conventional models, encompassing ex vivo models of thrombosis approaches that closely mimic the in vivo environment. By offering diverse models, including animal models, we facilitate a comprehensive understanding of thrombosis, from its initiation to the development of potential interventions.
For example, by using animal models to study the effects of injuries and flow conditions on thrombosis, providing further insight into how these factors contribute to thrombosis, we can develop more effective treatments for DVT and other thrombotic disorders.
Partnering with Porsolt for Thrombosis Insights
Porsolt is a trusted partner in preclinical research, collaborates closely with you to tailor our models and services to meet specific project needs. Our commitment to scientific excellence is evident in our rigorous methodologies, state-of-the-art facilities, and experienced team. Whether investigating deep vein thrombosis risk factors, screening compounds for anti-thrombotic potential, or analyzing histological and bioanalytical profiles, our comprehensive approach empowers researchers to drive advancements in thrombosis research.
Our histology labs offer a range of services for investigating the formation and growth of blood clots. We can analyze tissue samples from models in research, patients, and preclinical trials to identify the underlying causes of thrombosis and to assess the efficacy of new drugs and devices.
Our ex vivo models of thrombosis allow us to study the effects of blood flow, injuries, and other factors on thrombus formation. We can also use these models to test new drugs and devices for their ability to prevent or dissolve blood clots.
We are committed to advancing the understanding of thrombosis and developing new therapies for this serious condition. We believe that our expertise and innovative approaches can make a real difference in the lives of patients.
For more information about our thrombosis models and how we can support your specific project’s needs, please visit our website or contact us.
